Welcome to Living Proof

The Intracept Procedure is supported by strong scientific evidence, including two Level I randomized clinical trials. But the true proof is the living it has restored. You’ll find both kinds of proof here.

The Data Is Living Proof, Too

The Intracept Procedure is supported by unparalleled clinical evidence.

  • Four clinical studies that include two Level I randomized controlled trials.
  • Study results published in 10 peer-reviewed articles across 7 peer-reviewed journals, with additional systematic reviews and society guidelines on BVN ablation.

Proven Results


  • Long-term improvements in pain and function, sustained more than 5 years1
  • Sustained decrease in patients using opioids and injections long-term1
  • Nearly 80% of patients indicated they would have the procedure again for the same condition1
  • Less than 0.3% rate of serious Intracept Procedure-related complications reported.2
ODI Baseline Chart

Functional improvement.

Statistically sustained improvements in Oswestry Disability Index (ODI – a measure of function) shown 5 years post-procedure.1

Pain reduction.

Statistically significant reductions in Visual Analog Scale (VAS – a measure of pain) shown 5 years post-procedure.1

Fewer injections.

At 5 years post-procedure, 93% fewer patients had received injections.1

Fewer opioids.

At 5 years post-procedure, 73% fewer patients were actively using opioids.1

Take the Next Step

Find a Doctor

In a few steps, see if you may benefit from the procedure, and connect with an Intracept-trained physician near you.

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Join the Intracept Physician Community

Add the Intracept Procedure to your practice, gaining the clinical support, peer expertise, and program development resources needed to bring Living Proof to your patients.

As with any surgical procedure, there are risks and considerations associated with the Intracept Procedure. See important safety information below.

Patients: See the Indications & Risks Involved

The Intracept® Procedure is indicated for patients who have had chronic low back pain for at least six months, who have tried conservative care for at least six months, and whose MRI shows features consistent with Modic changes – indicating damage at the vertebral endplates has led to inflammation.

Not every patient who meets these criteria is a candidate for the Intracept Procedure, however – in fact, there are specific characteristics indicating a patient should not be considered for the procedure. These contraindications include being pregnant, having weakened cardiac or pulmonary function, having an implanted electronic medical device in the body (such as a pacemaker or defibrillator), being diagnosed with a systemic or local infection, or having an anatomy that could be damaged unintentionally while ablating the basivertebral nerve (based on your physicians’ clinical review). The Intracept Procedure is also contraindicated in patients who are skeletally immature – which generally means individuals under the age of 18 are not candidates. There are also certain risks and precautions regarding the procedure which you should be aware of before proceeding.

Talk with your doctor about what indicates, and contraindicates, certain patients for the Intracept Procedure – as well as the risks and precautions for the procedure.

Physicians: See Indications, Contraindications, and Risks

The Intracept Procedure Intraosseous Nerve Ablation System is intended to be used in conjunction with radiofrequency (RF) generators for the ablation of basivertebral nerves of the L3 through S1 vertebrae for the relief of chronic low back pain of at least six months duration that has not responded to at least six months of conservative care, and is also accompanied by features consistent with Type 1 or Type 2 Modic changes on an MRI such as inflammation, edema, vertebral endplate changes, disruption and fissuring of the endplate, vascularized fibrous tissues within the adjacent marrow, hypointensive signals (Type 1 Modic change), and changes to the vertebral body marrow including replacement of normal bone marrow by fat, and hyperintensive signals (Type 2 Modic change).

Use of the Intracept Procedure Intraosseous Nerve Ablation System is contraindicated in:

  • Patients with severe cardiac or pulmonary compromise
  • Patients where the targeted ablation zone is < 10 mm away from a sensitive structure not intended to be ablated, including the vertebral foramen (spinal canal)
  • Patients with active systemic infection or local infection in the area to be treated
  • Patients who are pregnant
  • Skeletally immature patients (generally < 18 years of age)
  • Patients with implantable pulse generators (e.g., pacemakers, defibrillators) or other electronic implants
  • Situations where unintended tissue damage may result, based on the clinical assessment by the physician
  • Application with electrosurgical instruments NOT tested and specified for use with the Relievant RFG

As with any surgical procedure, there are risks and considerations associated with the Intracept Procedure. To review the contraindications, warnings, and precautions click here.

  1. Fischgrund J, Rhyne A, Macadaeg K, et al. Long-term outcomes following intraosseous basivertebral nerve ablation for the treatment of chronic low back pain: 5-year treatment arm results from a prospective randomized double-blind sham-controlled multi-center study. Eur Spine J. 2020;29(8):1925-34. doi.org/10.1007/s00586-020-06448-x
  2. Relievant data on file.