The August issue of Pain Medicine includes several peer-reviewed articles focusing on vertebrogenic pain – defining patient, clinical, and imaging factors associated with basivertebral nerve (BVN) ablation treatment success following the Intracept Procedure; and a systematic review with a single-arm meta-analysis examining the effectiveness of BVN ablation to treat vertebrogenic low back pain.
This research confirms that:
- Vertebrogenic pain is a type of anterior column pain, resulting from accumulated damage to the “discovertebral” complex
- Patients successfully treated with the Intracept Procedure report similar patterns of pain presentation, including midline pain that is worse with physical activity, sitting and forward flexion
- Patients with even small, localized regions of Modic changes respond to basivertebral nerve ablation.
- Modic changes are the only known objective biomarker for vertebrogenic pain
The articles include:
- Vertebrogenic Pain: A Paradigm Shift in Diagnosis and Treatment of Axial Low Back Pain
- The Relationship Between Patient Demographic and Clinical Characteristics and Successful Treatment Outcomes After Basivertebral Nerve Radiofrequency Ablation: A Pooled Cohort Study of Three Prospective Clinical Trials
- Pain Location and Exacerbating Activities Associated with Treatment Success Following Basivertebral Nerve Ablation: An Aggregated Cohort Study of Multicenter Prospective Clinical Trial Data
- Magnetic Resonance Imaging Characteristics Associated with Treatment Success from Basivertebral Nerve Ablation: An Aggregated Cohort Study of Multicenter Prospective Clinical Trials Data
- The Effectiveness of Intraosseous Basivertebral Nerve Radiofrequency Ablation for the Treatment of Vertebrogenic Low Back Pain: An Updated Systematic Review with Single-Arm Meta-analysis